Institute for Stem Cell & Regenerative Medicine

A fluorescent microscopic image of a spherical cell cluster showing bright red, green, yellow, and blue regions, highlighting various cellular structures on a black background.

ISCRM Researchers Use AI-Designed Protein to Produce More Mineralized Enamel

ISCRM researchers have shown that an AI-designed signaling protein (known as a ligand) can be used to mature ameloblasts capable of secreting more mineralized enamel, representing another important step forward for regenerative dentistry.
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Dr. Jennifer Davis Named New ISCRM Director

Exciting leadership news! Dr. Jennifer Davis has been named the new Director of the Institute for Stem Cell and Regenerative Medicine
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Fluorescent microscopic image of EpiBinders-treated stem cells, showing clusters with cells stained in green, red, and blue, indicating different cellular components or markers. Text reads: EpiBinders-treated Stem Cells.

New $8.6M NIH RC2 Grant for an Interdisciplinary Team of ISCRM Faculty.

An interdisciplinary team of ISCRM researchers has received an $8.6 million grant from the NIH to accelerate cell therapies for diabetes by achieving more reliable and reproducible generation of fully functional pancreatic islets from multiple stem cell lines.
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Fluorescent microscopy image showing clusters of cells with blue nuclei, magenta cytoplasm, and green structures. The colors highlight different cell components in a tissue sample, likely used for biological or medical research.

Harnessing Early Progenitors to Grow Healthy Kidney Tissue Inside the Body

The Freedman Lab used a single pool of stem cells to generate multiple cell types crucial for kidney function and showed it may be more effective to kickstart this process in vivo instead of engineering tissue outside the body for transplantation.
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A colorful, abstract 3D visualization of clustered organic shapes, radiating outward from two central white ovals, resembling a scientific or microscopic model against a black background.

Stevens Lab Reconstructs Human Liver Tissue Cell Architecture in 3D

ISCRM faculty member Kelly Stevens is the senior author of a study, published in Science Advances, that unveils 3D reconstructions of human liver tissue offering unprecedented detail at the cellular level.
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